Six of us rented this house for a friend's wedding at the Seabrook Beach club, and it was terrific! The owner, Liz, is very helpful and communicative, and the house is clean and well maintained, with tasteful beach house decor. The layout of the main room of the condo is open and spacious, and the floor-to-ceiling windows look out onto a peaceful woodsy view.
The weather didn't cooperate the first day, but we found hanging out in the house very comfortable. And when it did shape up, we ran on the gorgeous beach (which can be accessed very close to the condo), had our morning coffee on one of the multiple porches, and walked over to the pool at the Seabrook club (where there are separate adult & kid pools and they make delicious pina coladas).
I would definitely recommend staying here, and if we ever find ourselves in Seabrook Island again, we'll be back!